Placental cadmium, genetic variations, and birth size
نویسندگان
چکیده
منابع مشابه
Prenatal Exposure to Cadmium, Placental Permeability and Birth Outcomes in Coastal Populations of South Africa
BACKGROUND The impact of prenatal exposure to cadmium (Cd) on birth outcomes is an area of concern. This study aimed to assess an impact of prenatal Cd exposure on birth outcomes in distinct coastal populations of South Africa. METHODS Cadmium was measured in maternal blood (CdB) (n = 641), cord blood and in maternal urine (n = 317). This investigation assessed the associations between CdB (n...
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The genetic architecture of placental abruption (PA) remains poorly understood. We examined variations in SNPs of circadian clock-related genes in placenta with PA risk. We also explored placental and maternal genomic contributions to PA risk. Placental genomic DNA samples were isolated from 280 PA cases and 244 controls. Genotyping was performed using the Illumina Cardio-MetaboChip. We examine...
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Altered placental function as a consequence of aberrant imprinted gene expression may be one mechanism mediating the association between low birth weight and increased cardiometabolic disease risk. Imprinted gene expression is regulated by epigenetic mechanisms, particularly DNA methylation (5mC) at differentially methylated regions (DMRs). While 5-hydroxymethylcytosine (5hmC) is also present a...
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BACKGROUND Cadmium (Cd) is an embryotoxic and teratogenic metal in a variety of animal species, but data from humans are limited. OBJECTIVES The aim of the present study was to assess the effects of maternal Cd exposure in pregnancy on size at birth. METHODS This prospective cohort study was nested in a population-based nutritional supplementation trial in pregnancy conducted in rural Bangl...
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Data obtained during 4 generations of divergent selection for placental efficiency were used to determine factors influencing survival at farrowing and weaning in litters produced by first-parity females. Data were collected from 193 litters and included records on 2,053 individuals. Farrowing survival (FS) and weaning survival (WS) were considered traits of the piglet and were scored 1 if the ...
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ژورنال
عنوان ژورنال: ISEE Conference Abstracts
سال: 2020
ISSN: 1078-0475
DOI: 10.1289/isee.2020.virtual.p-0536